SPM Active – Pro-Resolving Mediators for Immune & Inflammation Support
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Estimated Delivery:May 13 - May 17
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Free Shipping: On all orders over $50
Pick-up: Available in 2-4 business days

SPM Active – Pro-Resolving Mediators for Immune & Inflammation Support
SPM Active – Pro-Resolving Mediators for Immune & Inflammation Support
Product Overview
SPM Active by Metagenics, available at Rock Ridge Pharmacy, is a specialized immune support formula featuring standardized pro-resolving mediators (SPMs) derived from marine lipids. These SPMs—specifically 18-HEPE and 17-HDHA—support the body’s natural response to physical challenges by promoting the resolution phase of the immune response, not just inflammation suppression.
Unlike traditional fish oil supplements, SPM Active delivers targeted fractions of EPA and DHA derivatives that help return tissues to homeostasis following immune activation. This formula is ideal for individuals recovering from physical stress, injury, or chronic immune imbalances.
SPM Active – Key Benefits
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Promotes the body’s natural ability to resolve inflammation
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Supports immune system balance during physical recovery
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Features standardized SPMs (18-HEPE and 17-HDHA) from marine lipid concentrate
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Non-GMO, gluten-free, and sustainably sourced
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Backed by TruQuality® testing for purity and potency
Ingredients & Nutritional Profile
Serving Information
Serving Size: 2 Softgels
Servings Per Container: 30
Key Ingredient
Ingredient | Amount Per Serving | Key Benefits |
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Active Fractionated Marine Lipid Concentrate† | 1 g | Provides specialized pro-resolving mediators (SPMs) to help restore immune balance |
— Standardized to 18-HEPE and 17-HDHA | — | Supports resolution of the immune response after inflammation |
Other Ingredients
Fractionated marine lipid concentrate [fish oil from anchovy, sardine, and mackerel, with mixed tocopherols (antioxidant)], softgel shell (gelatin, glycerin, water), silica
Contains: Fish (anchovy, sardine, mackerel)
Does Not Contain
Gluten, GMOs, dairy, soy, or artificial preservatives
How to Take SPM Active
Dosage: Take 2 softgels once daily or as directed by your healthcare practitioner
Best Time to Take: With meals for optimal absorption of omega-based lipids
Who Should Avoid It?
Consult your healthcare provider if you are pregnant, nursing, or taking medications or other supplements. Not suitable for those with fish allergies. Keep out of reach of children.
Frequently Asked Questions (FAQs)
1. What are SPMs and how are they different from fish oil?
SPMs (Specialized Pro-Resolving Mediators) are derivatives of omega-3 fatty acids that actively support the resolution of inflammation. Unlike general fish oil, SPM Active delivers concentrated and standardized SPMs for targeted immune support.
2. Is this product safe for long-term use?
Yes, when taken as directed, SPM Active is safe and supportive for long-term immune balance and recovery.
3. Can this help with joint or muscle recovery?
Yes, it supports the body’s natural response after physical stress, which may benefit joints, tissues, and muscles.
4. Is it tested for purity?
Yes, each batch is tested under the Metagenics TruQuality® program to ensure purity and potency.
5. Is it suitable for people with inflammation-related health concerns?
Yes, SPM Active may help support balanced immune activity in individuals experiencing chronic or unresolved inflammation.
Why Buy from Rock Ridge Pharmacy?
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Professional-grade immune and inflammation support formulas
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Backed by licensed pharmacist consultation and expertise
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Fast shipping, trusted service, and quality-guaranteed products
Order SPM Active Today – Only at Rock Ridge Pharmacy
Target inflammation resolution and support immune balance naturally with clinically relevant pro-resolving mediators.
Available now – Shop confidently at Rock Ridge Pharmacy!